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A Schiff Base Is a Major DNA Adduct of Crotonaldehyde

✍ Scribed by McIntee, Edward J.; Cheng, Guang; Shi, Yongli; Villalta, Peter W.; Hecht, Stephen S.; Wang, Mingyao


Book ID
111902384
Publisher
American Chemical Society
Year
2001
Tongue
English
Weight
175 KB
Volume
14
Category
Article
ISSN
0893-228X

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## Abstract A bulky DNA adduct (Spot 1) was previously detected in normal adjacent breast tissues of 41% (36/87) of women with breast cancer and in none (0/29) of the noncancer controls by ^32^P‐postlabeling. To characterize this adduct, it was chromatographically compared with DNA adduct profiles