A scaling normalization method for diffe
โ
Robinson, Mark D; Oshlack, Alicia
๐
Article
๐
2010
๐
BioMed Central
๐
English
โ 655 KB
The fine detail provided by sequencing-based transcriptome surveys suggests that RNA-seq is likely to become the platform of choice for interrogating steady state RNA. In order to discover biologically important changes in expression, we show that normalization continues to be an essential step in t