First asymmetric synthesis of (2R, 3R)-3
β
Pei Qiang Huang; Si Li Wang; Hong Zheng; Xiang Su Fei
π
Article
π
1997
π
Elsevier Science
π
French
β 117 KB
The first asymmetric synthesis of (2R, 3R)-3-amino-l-benzyl-2-methylpyrrolidine, the parent diamine of antipsychotic agent, emonapride, from (S)-malic acid was achieved via a highly diastereroselective reductive alkylation.