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A Scalable Asymmetric Synthesis of ( R )-2-Amino-1-(3-pyridinyl)ethanol Dihydrochloride via an Oxazaborolidine Catalyzed Borane Reduction

✍ Scribed by Duquette, Jason; Zhang, Mingbao; Zhu, Lei; Reeves, Raymond S.


Book ID
126141888
Publisher
American Chemical Society
Year
2003
Tongue
English
Weight
62 KB
Volume
7
Category
Article
ISSN
1083-6160

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πŸ“œ SIMILAR VOLUMES


First asymmetric synthesis of (2R, 3R)-3
✍ Pei Qiang Huang; Si Li Wang; Hong Zheng; Xiang Su Fei πŸ“‚ Article πŸ“… 1997 πŸ› Elsevier Science 🌐 French βš– 117 KB

The first asymmetric synthesis of (2R, 3R)-3-amino-l-benzyl-2-methylpyrrolidine, the parent diamine of antipsychotic agent, emonapride, from (S)-malic acid was achieved via a highly diastereroselective reductive alkylation.

Corrigendum to β€œFirst asymmetric synthes
✍ Pei Qiang Huang; Shi Li Wang; Hong Zheng; Xiang Su Fei πŸ“‚ Article πŸ“… 2001 πŸ› Elsevier Science 🌐 French βš– 31 KB

The authors regret that on page 271 the second author name was spelt incorrectly and should read as ''Shi Li Wang''. ## The value for [h] D of compound 6 on page 271 is also incorrect and should read as follows: [h] D 20 -83.9 (c 1.1 in CHCl 3 ).