✦ LIBER ✦

A Route to Optically Active Trisubstituted Pyrrolidines using Claisen Rearrangements of Azalactones.

✍ Scribed by Jeremy Cooper; David W Knight; Peter T Gallagher

Publisher: Elsevier Science
Year: 1987
Tongue: French
Weight: 238 KB
Volume: 28
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(00)96277-4

No coin nor oath required. For personal study only.

✦ Synopsis

Chiral trisubstituted pyrrolidines [(13a) and (13b)l are obtained exclusively by Ireland enolate Claisen rearrangement of the corresponding azalactones [(12a) and (12b)l.