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A role of lyso-phosphatidylcholine in GM3-dependent inhibition of epidermal growth factor receptor autophosphorylation in A431 plasma membranes

✍ Scribed by Yasuyuki Igarashi; Kazuya Kitamura; Qinghong Zhou; Sen-itiroh Hakomori

Book ID
117054923
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
986 KB
Volume
172
Category
Article
ISSN
0006-291X

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✍ Ann Mangelsdorf Soderquist; Christa Stoscheck; Graham Carpenter πŸ“‚ Article πŸ“… 1988 πŸ› John Wiley and Sons 🌐 English βš– 846 KB

We have studied the synthesis and oligosaccharide processing of the 110,000 dalton form of the epidermal growth factor (EGF) receptor that is secreted into the medium of A-431 cells. Its 90,000 dalton precursor is soluble within the lumen of intracellular membrane vesicles shortly after synthesis, i