We examined cytokine-mediated neuronal death in neuron-astrocyte cultures from second trimester human fetal cerebrum. In these cultures, high-output inducible nitric oxide synthase (NOS) and tumor necrosis factor-␣ (TNF␣) are expressed in astrocytes after exposure to IL-1/IFN␥. Neuronal cell death
✦ LIBER ✦
A Role for Tumor Necrosis Factor α in Death of Dopaminergic Neurons Following Neural Transplantation
✍ Scribed by Deborah J. Clarke; Richard L. Branton
- Book ID
- 115607735
- Publisher
- Elsevier Science
- Year
- 2002
- Tongue
- English
- Weight
- 277 KB
- Volume
- 176
- Category
- Article
- ISSN
- 0014-4886
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## membrane barrier function in the late phase. (HEPATOL-Kupffer cells have been implicated in playing an im- OGY 1996;24:1185-1192.) portant role in the pathogenesis of endotoxemia-associated liver injury. The present study was designed to investigate whether Kupffer cell-derived mediators alter