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A Role for the Plasminogen Activator System in Inflammation and Neurodegeneration in the Central Nervous System during Experimental Allergic Encephalomyelitis

✍ Scribed by Emma East; David Baker; Gareth Pryce; H. Roger Lijnen; M. Louise Cuzner; Djordje Gverić

Book ID
117021417
Publisher
American Society for Investigative Pathology
Year
2005
Tongue
English
Weight
905 KB
Volume
167
Category
Article
ISSN
0002-9440

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In the central nervous system (CNS), p75, or lowaffinity nerve growth factor receptor (LNGFR), is assumed to play a critical role in mediating the effects of neurotrophins on neuronal survival. Recent studies have shown that nerve growth factor (NGF) can act also on immune cells through its binding