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A role for the neurotrophin receptor TrkB on maturing dendritic cells

✍ Scribed by Kai Bratke; Lars Maruschke; Martin Darowski; Michael Kuepper; Armin Braun; J. Christian Virchow; Marek Lommatzsch

Book ID
113730135
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
619 KB
Volume
189
Category
Article
ISSN
0165-5728

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The tyrosine kinase TrkB is a receptor for the neurotrophic factors brain-derived neurotrophic factor (BDNF) and neurotrophin-4 (NT-4). Retinal ganglion cells are responsive to BDNF, and TrkB has been localized in ganglion cells as well as in a subpopulation of amacrine cells in the retina of the ch