We have previously demonstrated that elevated Fos expression may be important in de novo endocrine resistance in breast cancer. However, changes in Fos expression during endocrine response and subsequently on acquisition of resistance are unknown. This study immunocytochemically monitors Fos protein
A role for the MARK activated transcription factor PEA3 in HER2 regulation in human thyroid cancer
✍ Scribed by D. O. Kavanagh; E. Myers; C. O’Riain; T. B. Crotty; E. W. McDermott; N. J. O’Higgins; A. D. K. Hill; L. S. Young
- Publisher
- Springer-Verlag
- Year
- 2005
- Tongue
- English
- Weight
- 320 KB
- Volume
- 174
- Category
- Article
- ISSN
- 1863-4362
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
This paper describes the generation and characterization of a monoclonal antibody specific for two members of the AP-2 family of transcription factors, AP-2 and AP-2 , and its subsequent application to archival primary breast tumour material. Nuclear localization of AP-2 was found in all expressing
Cyclin-dependent kinase inhibitors play a significant role in cell cycle progression and in cellular differentiation and their expression is regulated in different cellular settings. GC-rich regions in the promoter sequences of the cyclin-dependent kinase inhibitor genes p15INK4B and p21CIP1/WAF1 me
## Abstract Prostaglandin F2α (PGF2α) is a potent paracrine inhibitor of adipocyte differentiation. Here we show that treatment of differentiating 3T3‐L1 preadipocytes with PGF2α induces the expression of DEC1, a transcriptional repressor that has previously been implicated in the inhibition of adi
## Abstract Supernatants from freshly disaggregated human ovarian carcinomas maintained __in vitro__ for 24 hr, from primary ovarian carcinoma cultures (4–6 days in culture) and from established ovarian cancer cell lines were examined for chemotactic activity on blood monocytes in blind‐well chemot