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A Role for PML3 in Centrosome Duplication and Genome Stability

✍ Scribed by Zhi-Xiang Xu; Wen-Xin Zou; Pei Lin; Kun-Sang Chang


Book ID
116753802
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
753 KB
Volume
17
Category
Article
ISSN
1097-2765

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The centrosome must be replicated once, and only once, during each cell cycle. To achieve this somatic cells need to synthesize centrosome proteins, target those centrosome proteins to the parental centrosome, and then assemble the centrosome subunits into a functional organelle. The mechanisms that