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A role for lipid rafts in C1q-triggered O2− generation by human neutrophils

✍ Scribed by Iyore Otabor; Shivraj Tyagi; Frank J.M Beurskens; Ionita Ghiran; Pascale Schwab; Anne Nicholson-Weller; Lloyd B Klickstein

Book ID
116755327
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
275 KB
Volume
41
Category
Article
ISSN
0161-5890

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Intercellular adhesion molecule 1 and β2
Intercellular adhesion molecule 1 and β2 integrins in C1q-stimulated superoxide production by human neutrophils: An example of a general regulatory mechanism governing acute inflammation
✍ Shivraj Tyagi; Anne Nicholson-Weller; Sergei F. Barbashov; Sander W. Tas; Lloyd 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 178 KB

## Objective: To investigate the role of intercellular adhesion molecule 1 (icam-1) and beta2 integrins in the production of superoxide (o2-) by c1q-stimulated human polymorphonuclear leukocytes (pmn). ## Methods: Pmn were pretreated with f(ab')2 fragments of monoclonal antibodies (mab) that bloc