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A ribosome-like particle accumulated at low temperature by a cold-sensitive mutant of Salmonella typhimurium

✍ Scribed by Phang-Cheng Tai; John L. Ingraham


Book ID
115744353
Publisher
Elsevier Science
Year
1971
Weight
853 KB
Volume
232
Category
Article
ISSN
0005-2787

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A cold sensitive dnaA mutant of E. coli
✍ Kellenberger-Gujer, G. ;Podhajska, A. J. ;Caro, L. πŸ“‚ Article πŸ“… 1978 πŸ› Springer 🌐 English βš– 738 KB

A heat resistant mutant of E. coli dnaAts46 was isolated, which grows normally only at temperatures above 39 degrees. After a temperature shift from 42 degrees to 32 degrees the mutant overproduces DNA relative to protein. This is due to overinitiation of rounds of chromosome replication at low temp