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A ribosome-associated inhibitor of in vitro nonsense suppression in [psi−] strains of yeast

✍ Scribed by Mick F. Tuite; Brain S. Cox; Calvin S. McLaughlin

Book ID
115919791
Publisher
Elsevier Science
Year
1987
Tongue
English
Weight
859 KB
Volume
225
Category
Article
ISSN
0014-5793

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When a [psi-] strain of yeast mutates to [psi+], the efficiency of suppression by certain ochre suppressors is increased. The [psi+] phenotype is inherited extrachromosomally. There is a nuclear gene, PNM, which, when mutant, causes loss of the [psi+] phenotype. PNM- is dominant to PNM+ and a hetero