A rhodamine-based Hg2+-selective fluorescent probe in aqueous solution

✍ Scribed by Minglei Zhao; Xiao-Feng Yang; Shenfeng He; Liping Wang

• Book ID: 111491234
• Publisher: Versita
• Year: 2009
• Tongue: English
• Weight: 356 KB
• Volume: 63
• Category: Article
• ISSN: 0366-6352
• DOI: 10.2478/s11696-009-0016-8

✦ Synopsis

Abstract

A new rhodamine-based Hg2+-selective fluorescent probe (I) was designed and synthesized. Compound I displays excellent selective and sensitive response to Hg2+ over other transition metal ions in neutral aqueous solutions. I itself is a colorless, nonfluorescent compound. Upon addition of Hg2+ to its solution, the thiosemicarbazide moiety of I undergoes an irreversible desulfurization reaction to form the corresponding 1,3,4-oxadiazole (II), a colorful and fluorescent product, causing instantaneous development of visible color and strong fluorescence emission. Based on this mechanism, a fluorogenic probe for Hg2+ was developed. The fluorescence increases linearly with the Hg2+ concentration up to 0.8 μmol L−1 with the detection limit of 9.4 nmol L− (3σ).