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A review of the relevance and validity of olfactory bulbectomy as a model of depression

✍ Scribed by Andrew Harkin; John P Kelly; Brian E Leonard

Book ID
114414380
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
166 KB
Volume
3
Category
Article
ISSN
1566-2772

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The olfactory bulbectomised rat as a mod
The olfactory bulbectomised rat as a model of depression
✍ Cai Song; Brian E. Leonard πŸ“‚ Article πŸ“… 2005 πŸ› Elsevier Science 🌐 English βš– 357 KB

Bilateral olfactory bulbectomy results in changes in behavior, and in the endocrine, immune and neurotransmitter systems, that simulates many of those seen in patients with major depression. The olfactory system in the rat forms a part of the limbic region in which the amygdala and hippocampus contr