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A review of lipidomic technologies applicable to sphingolipidomics and their relevant applications

โœ Scribed by Xianlin Han; Xuntian Jiang

Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
430 KB
Volume
111
Category
Article
ISSN
1438-7697

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โœฆ Synopsis

Abstract

Sphingolipidomics, a branch of lipidomics, focuses on the largeโ€scale study of the cellular sphingolipidomes. In the current review, two main approaches for the analysis of cellular sphingolipidomes (i.e. LCโ€MSโ€ or LCโ€MS/MSโ€based approach and shotgun lipidomicsโ€based approach) are briefly discussed. Their advantages, some considerations of these methods, and recent applications of these approaches are summarized. It is the authors' sincere hope that this review article will add to the readers understanding of the advantages and limitations of each developed method for the analysis of a cellular sphingolipidome.

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