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A review of in vitro and in vivo culture techniques for the study of pancreatic carcinogenesis

✍ Scribed by Raymond T. Jones; Eric A. Hudson; James H. Resau


Publisher
John Wiley and Sons
Year
1981
Tongue
English
Weight
974 KB
Volume
47
Category
Article
ISSN
0008-543X

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✦ Synopsis


Techniques have been developed for long-term organ explant culture of bovine, hamster, and human pancreatic ducts in enriched medium. The explants were then exposed to chemical carcinogens and studied by morphologic and biochemical techniques. Untreated explants have also been successfully xenotransplanted into athymic "nude" mice. Techniques have also been developed to isolate human and bovine pancreatic ductal cells for cell culture. These as well as techniques developed by other authors are discussed.


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