We evaluated the accuracy of ultrasonographic diagnosis of autosomal dominant polycystic kidney disease (ADPKD) and factors influencing its prognosis in members of 17 Newfoundland families originally described in 1984. In 10 families showing genetic linkage between ADPKD and markers for the PKDl loc
A “reverse genetic” approach to autosomal dominant polycystic kidney disease
✍ Scribed by Stephen T. Reeders
- Publisher
- Springer
- Year
- 1987
- Tongue
- English
- Weight
- 602 KB
- Volume
- 1
- Category
- Article
- ISSN
- 0931-041X
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📜 SIMILAR VOLUMES
The results of classical segregation analysis on 159 families with polycystic kidney disease (PKD) are presented. It had been previously estimated that about 95% of autosomal dominant PDK (ADPKD) families have PKD 1, the gene localized to chromosome 16p. The main purpose of the study was to determin
Autosomal dominant polycystic kidney disease (ADPKD) arises from mutations in the PKD1 and PKD2 genes. The Polycystic Kidney Disease Mutation Database (PKDB) is an internet-accessible relational database containing comprehensive information about germline and somatic disease-causing variants within