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A retrovirus restriction factor TRIM5α is transcriptionally regulated by interferons

✍ Scribed by Kentaro Asaoka; Kazuhiro Ikeda; Toshiki Hishinuma; Kuniko Horie-Inoue; Satoru Takeda; Satoshi Inoue


Book ID
116291761
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
298 KB
Volume
338
Category
Article
ISSN
0006-291X

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## Abstract Tumor necrosis factor (TNF)‐α is known for its osteoclastogenic and resorptive activities. Induction of osteoclastogenesis by receptor activator of NF‐κB ligand (RANKL) is accompanied by increased TNF‐α expression. In the present study we investigated the mechanism by which RANKL induce