A transgenic mouse model of the slow-cha
✍
Christopher M. Gomez; Bula B. Bhattacharyya; Pierre Charnet; John W. Day; Cesar
📂
Article
📅
1996
🏛
John Wiley and Sons
🌐
English
⚖ 861 KB
To investigate the effect of acetylcholine receptor (AChR) mutations on neuromuscular transmission and to develop a model for the human neuromuscular disease, the slow-channel syndrome, we generated transgenic mice with abnormal AChRs using a 6 subunit with a mutation in the ion channel domain. In t