A retrospective analysis of the clinicopathologic characteristics of uterine cellular leiomyomas in China
β Scribed by Rui Guan; Weiqiang Zheng; Mingjuan Xu
- Book ID
- 116555660
- Publisher
- Elsevier Science
- Year
- 2012
- Tongue
- English
- Weight
- 360 KB
- Volume
- 118
- Category
- Article
- ISSN
- 0020-7292
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Uterine leiomyomas are benign tumors that arise clonally from smooth muscle cells of the myometrium. Cytogenetic studies of uterine leiomyomas have shown that about 40% have chromosome abnormalities and that deletion of 7q is a common finding. The observations suggest the possible location of a grow
## Abstract Leiomyomas are the most common gynecologic tumors in women, but very little is known about their molecular pathology. We used singleβstranded conformational polymorphism/heteroduplex analysis to analyze 42 unselected uterine leiomyomas for somatic mutations in all coding exons of the ge