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A Regularized Hotelling’s T 2 Test for Pathway Analysis in Proteomic Studies

✍ Scribed by Chen, Lin S.; Paul, Debashis; Prentice, Ross L.; Wang, Pei


Book ID
126868421
Publisher
American Statistical Association
Year
2011
Tongue
English
Weight
821 KB
Volume
106
Category
Article
ISSN
0162-1459

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Suppose that \(Y\) is distributed as multivariate normal with unknown covariance matrix and that \(N\) independent observations are available on \(Y\). An important special case of the problem studied in this paper is that of testing the null hypothesis that the mean of \(Y\) is zero against the alt