## Abstract The purpose of this study is to examine the relationship between dioxin concentration in humans and their living environmental factors such as diet or residential district. We develop a nonlinear random effects regression model based on a pharmacokinetic model that explains dioxin accum
A regression model for multivariate random length data
β Scribed by Huiman X. Barnhart; Andrzej S. Kosinski; Allan R. Sampson
- Publisher
- John Wiley and Sons
- Year
- 1999
- Tongue
- English
- Weight
- 109 KB
- Volume
- 18
- Category
- Article
- ISSN
- 0277-6715
No coin nor oath required. For personal study only.
β¦ Synopsis
Multivariate random length data occur when we observe multiple measurements of a quantitative variable and the variable number of these measurements is also an observed outcome for each experimental unit. For example, for a patient with coronary artery disease, we may observe a number of lesions in that patient's coronary arteries, along with percentage of blockage of each lesion. Barnhart and Sampson ΓΏrst proposed the multiple population model to analyse multivariate random length data without covariates. This paper extends their approach to deal with multiple covariates. We propose a new multiple population regression model with covariates, and discuss the estimation issues. We analyse data from the TYPE II coronary intervention study to illustrate the methodology.
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