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A Reexamination of Inductive Substituent Constants Derived from pKa Values of 4-Substituted Quinuclidines. Polar effects. Part VIII

✍ Scribed by Cyril A. Grob; Bruno Schaub; Markus G. Schlageter


Publisher
John Wiley and Sons
Year
1980
Tongue
German
Weight
315 KB
Volume
63
Category
Article
ISSN
0018-019X

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✦ Synopsis


Abstract

p__K__~a~ Values of 42 quinuclidinium perchlorates I have been measured in 0.1 M aqueous KCl‐solution. In a few cases small corrections of earlier thermodynamic p__K__~a~ values are indicated. These measurements, in conjunction with recent X‐ray structure determinations, confirm the reliability of the inductive substituent constants σ~I~^q^ derived from them.