A rational design approach for amino aci
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Hong Yang; Charles M. Roth; Marianthi G. Ierapetritou
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Article
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2009
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John Wiley and Sons
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English
β 636 KB
## Abstract Improvement of culture media for mammalian cells is conducted via empirical adjustments, sometimes aided by statistical design methodologies. Here, we demonstrate a proof of principle for the use of constraintsβbased modeling to achieve enhanced performance of liverβspecific functions o