A Rapid Synthesis of Oligopeptide Derivatives without Isolation of Intermediates
โ Scribed by Sheehan, John C.; Preston, John; Cruickshank, Philip A.
- Book ID
- 127139526
- Publisher
- American Chemical Society
- Year
- 1965
- Tongue
- English
- Weight
- 228 KB
- Volume
- 87
- Category
- Article
- ISSN
- 0002-7863
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๐ SIMILAR VOLUMES
A novel method was developed for the large-scale manufacture of peptides in solution, called DioRaSSP-Diosynth Rapid Solution Synthesis of Peptides. This method combines the advantages of the homogeneous character of classical solution-phase synthesis with the universal character and the amenability
## Abstract A series of protected Lโnorvaline homoโoligomers from dimer to heptamer was prepared by the dicyclohexylcarbodiimide and acid azide coupling methods. In the course of our synthetic approach tโbutyloxycarbonyl as the Nโprotecting and methyl ester as the Cโprotecting end groups were used.