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A rapid, sensitive method for the simultaneous quantitation of estradiol and estradiol conjugates in a variety of tissues: Assay development and evaluation of the distribution of a brain-enhanced estradiol-chemical delivery system

✍ Scribed by Mohamad H. Rahimy; Nicholas Bodor; James W. Simpkins


Book ID
116007554
Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
980 KB
Volume
33
Category
Article
ISSN
0022-4731

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## Abstract An ultra‐sensitive liquid chromatography/tandem mass spectrometry (LC/MS/MS) method for the analysis of oral contraceptive ethinyl estradiol (EE) was developed and validated over the curve range of 2.5–500 pg/mL using 1 mL of human plasma sample. Ethinyl estradiol and the internal stand