A rapid screening assay for measuring urinary androsterone and etiocholanolone δ13C (‰) values by gas chromatography/combustion/isotope ratio mass spectrometry

Determination of low isotopic enrichment

Determination of low isotopic enrichment ofL-[1-13C]valine by gas chromatography/combustion/isotope ratio mass spectrometry: a robust method for measuring protein fractional synthetic ratesin vivo

✍ Reijngoud, Dirk-Jan; Hellstern, Gerald; Elzinga, Henk; de Sain-van der Velden, M 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 225 KB 👁 1 views

A method was developed for measuring protein fractional synthetic rates using the N-methoxycarbonylmethyl ester (MCM) derivative of L-[ 1-13C ] valine and on-line gas chromatography/combustion/isotope ratio mass spectrometry (GC/C/IRMS). The derivatization procedure can be performed rapidly and GC s