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A rapid ‘one-plate’ in vitro test for pyrogens

✍ Scribed by Stephen Poole; Yogesh Mistry; Christine Ball; Rose E Gaines Das; Lisa Pieti Opie; Garry Tucker; Mehul Patel

Book ID
114051250
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
171 KB
Volume
274
Category
Article
ISSN
0022-1759

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## Abstract Medical devices manufactured for implantation into humans must be free of any contamination with viable bacteria. However, remnants of dead bacteria and bacterial components alone may induce an inflammatory immune response. Pyrogen tests for such inflammatory contaminations are generall