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A rapid method for targeted modification and screening of recombinant bacterial artificial chromosome

✍ Scribed by Ziva Misulovin; Xiangdong W Yang; Wong Yu; Nathaniel Heintz; Eric Meffre

Book ID
114050843
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
165 KB
Volume
257
Category
Article
ISSN
0022-1759

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## Abstract Summary: The Pax2 gene is expressed in the developing otocyst, kidney, and midbrain–hindbrain boundary. We generated Pax2‐Cre transgenic lines by modification of a Pax2 bacterial artificial chromosome (BAC). In one Pax2‐Cre line, Cre mRNA starts to be expressed in the otic placode at th