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A rapid determination of propiverine and its N-oxide metabolite in human plasma by high performance liquid chromatography–electrospray ionization tandem mass spectrometry

✍ Scribed by Kyung-Hwan Yoon; So-Young Lee; Mi Jang; Sook-Hyun Ko; Won Kim; Jong-sei Park; Insook Park; Hie-Joon Kim

Book ID
116901038
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
125 KB
Volume
66
Category
Article
ISSN
0039-9140

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## Abstract A rapid, sensitive and specific high‐performance liquid chromatography–electrospray ionization mass spectrometry (LC‐ESI‐MS) method has been developed and validated for the determination of oxatomide in human plasma. Flunarizine hydrochloride was employed as the internal standard (IS).