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A rapid and sensitive liquid chromatography-tandem mass spectrometric method for determination of actinoside E in rat plasma and application to a pharmacokinetic study

โœ Scribed by QU, Li-Ping; SU, Yong-Hua; ZHENG, Guo-Yin; XIN, Hai-Liang; LING, Chang-Quan


Book ID
121941275
Publisher
Elsevier
Year
2013
Tongue
Chinese
Weight
827 KB
Volume
11
Category
Article
ISSN
1875-5364

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Liquid chromatography-tandem mass spectr
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## Abstract A rapid LCโ€MS/MS method for quantification of an enaminone analog, E121 in mouse plasma using E118 as an internal standard (IS) has been developed and validated. The analyte was analyzed on C~18~ column using a mobile phase of acetonitrile/methanol/ammonium acetate/formic acid (60:20:20