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A rapid and sensitive HPLC–MS/MS analysis and preliminary pharmacokinetic characterization of sibiricaxanthone F in rats

✍ Scribed by Xiaojuan Yang; Guanshen Zhou; Pingping Zou; Ying Ning; Ke Zan; Pengfei Tu; Yong Jiang

Book ID
116620474
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
614 KB
Volume
879
Category
Article
ISSN
1873-376X

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## Abstract A rapid and sensitive quantitative assay method was developed for determining ribavirin pharmacokinetic in human plasma. The chromatographic separation was achieved within 4.5 min using a SinoChrom ODS‐BP column (4.6 × 150 mm, 5 µm) with acetonitrile–water (1 mmol/L ammonium acetate buf