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A rapid and sensitive HPLC–APCI-MS/MS method determination of fluticasone in human plasma: Application for a bioequivalency study in nasal spray formulations

✍ Scribed by Ricardo Martins Duarte Byrro; Isabela Costa César; Fabiana Fernandes de Santana e Silva Cardoso; Iram Moreira Mundim; Leonardo de Souza Teixeira; Ricardo Rodrigues Bonfim; Sandro Antônio Gomes; Gerson Antônio Pianetti

Book ID
113743265
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
543 KB
Volume
61
Category
Article
ISSN
0731-7085

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Determination of triamcinolone in human
Determination of triamcinolone in human plasma by a sensitive HPLC–ESI-MS/MS method: application for a pharmacokinetic study using nasal spray formulation
✍ Isabela Costa César; Ricardo Martins Duarte Byrro; Fabiana Fernandes de Santana 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 242 KB 👁 1 views

## Abstract A liquid chromatography–electrospray ionization tandem mass spectrometry (HPLC–ESI‐MS/MS) method for the quantitation of triamcinolone in human plasma after nasal spray application was developed and validated. Betamethasone was used as internal standard (IS). The analytes were extracted