✦ LIBER ✦

A randomized trial to assess the efficacy of surgery in addition to radiotherapy in patients with a single cerebral metastasis

✍ Scribed by Arlan H. Mintz; John Kestle; Michel P. Rathbone; Laurie Gaspar; Herman Hugenholtz; Barbara Fisher; Graeme Duncan; Peter Skingley; Gary Foster; Mark Levine

Publisher: John Wiley and Sons
Year: 1996
Tongue: English
Weight: 622 KB
Volume: 78
Category: Article
ISSN: 0008-543X
DOI: 10.1002/(sici)1097-0142(19961001)78:7<1470::aid-cncr14>3.0.co;2-x

No coin nor oath required. For personal study only.

✦ Synopsis

BACKGROUND. Cerebral metastasis is a common oncologic problem that occurs in

15-3096 of cancer patients; approximately half such metastases are single. Previous retrospective studies and two randomized trials reported that the addition of surgical extirpation prior to radiation therapy increased survival, neurologic function, and quality of life compared with radiation alone in patients with a single brain metastasis.

Agency, Vancouver Centre (G. Duncan); Ontario Clinical Oncology Group (M. Levine and P. Skingley).

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