A randomized trial of treatment for multisystem Langerhans’ cell histiocytosis
✍ Scribed by Helmut Gadner; Nicole Grois; Maurizio Arico; Valerie Broadbent; Adriana Ceci; Ake Jakobson; Diane Komp; Jörg Michaelis; Stacy Nicholson; Ulrike Pötschger; Jon Pritchard; Stephan Ladisch
- Book ID
- 117847629
- Publisher
- Elsevier Science
- Year
- 2001
- Tongue
- English
- Weight
- 108 KB
- Volume
- 138
- Category
- Article
- ISSN
- 1097-6833
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Background. Treatment of multisystem Langerhans cell histiocytosis (LCH) remains difficult. Various regimens of single and multiagent chemotherapy have been used, but a significant proportion of patients fail to respond to treatment. Procedure. We have evaluated the use of cyclosporine A (CSA) in a
## Abstract ## Background Reliable prediction of prognosis allowing risk‐adapted therapy remains a major issue in the management of multisystem Langerhans cell histiocytosis (LCH). In a recent publication of the International LCH Study Group, response to initial therapy appears to be a reliable ou