𝔖 Bobbio Scriptorium
✦   LIBER   ✦

A randomized trial of terlipressin plus nitroglycerin vs. balloon tamponade in the control of acute variceal hemorrhage

✍ Scribed by Eric Fort; Denis Sautereau; Christine Silvain; Pierre Ingrand; Bernard Pillegand; Pr. Michel Beauchant

Publisher
John Wiley and Sons
Year
1990
Tongue
English
Weight
526 KB
Volume
11
Category
Article
ISSN
0270-9139

No coin nor oath required. For personal study only.

✦ Synopsis

Unite' d'He'patologie CHU J. Bernard Poitiers and "Service d'He'patogastroente'rologie CHU Dupuytren Limoges

MICHEL BEAUCHANT'

A randomized trial was undertaken to determine the efficacy of nitroglycerin in addition to terlipressin infusion to improve the control of acute variceal hemorrhage compared with balloon tamponade. Fortyseven bleeding episodes in 34 cirrhotic patients were included, with terlipressin plus sublingual nitroglycerin in 23 episodes (group I) and balloon tamponade in 24 episodes (group 11). At the end of the 12-hr period, hemorrhage had been equally controlled in both groups (18 of 23; 78% in group I and 19 of 24; 79% in group 11). When attempted, balloon tamponade appeared more efficient in the failures of group I (4 of 4) than did terlipressin plus nitroglycerin in the failures of group I1 (0 of 3), although this difference was not significant. Major complications were rare (one in each group) and never required cessation of therapy. Thus terlipressin and nitroglycerin were as effective as balloon tamponade in controlling variceal hemorrhage and were associated with few minor complications. (HEPATOLOGY 199% 11:678-68 1.

πŸ“œ SIMILAR VOLUMES

Terlipressin plus transdermal nitroglyce
Terlipressin plus transdermal nitroglycerin vs. octreotide in the control of acute bleeding from esophageal varices: A multicenter randomized trial
✍ Christine Silvain; StΓ©phane Carpentier; Denis Sautereau; Bella Czernichow; Jean- πŸ“‚ Article πŸ“… 1993 πŸ› John Wiley and Sons 🌐 English βš– 640 KB

We undertook a multicenter randomized trial to compare the efficacy of terlipressin combined with transdermal nitroglycerin and that of octreotide in the emergency control of acute variceal hemorrhage in cirrhosis. Over 16 mo, 87 patients with endoscopically proved active bleeding from esophageal or

A randomized trial of vasopressin and va
A randomized trial of vasopressin and vasopressin plus nitroglycerin in the control of acute variceal hemorrhage
✍ Alexander E. S. Gimson; David Westaby; John Hegarty; Alastair Watson; Roger Will πŸ“‚ Article πŸ“… 1986 πŸ› John Wiley and Sons 🌐 English βš– 456 KB

A randomized trial was undertaken to determine efficacy of nitroglycerin when added to a vasopressin infusion in both reducing the complication rate and giving improved control of acute variceal hemorrhage. Seventy-two bleeding episodes in 57 patients were included, with vasopressin being used on 34

Vasopressin/nitroglycerin infusion vs. e
Vasopressin/nitroglycerin infusion vs. esophageal tamponade in the treatment of acute variceal bleeding: A randomized controlled trial
✍ Dr. Josep Teres; Ramon Planas; Julia Panes; Joan Manel Salmeron; Antoni Mas; Jai πŸ“‚ Article πŸ“… 1990 πŸ› John Wiley and Sons 🌐 English βš– 592 KB

Vasopressin infusion and esophageal tamponade are still widely used to arrest variceal bleeding, but no objective evidence exists on the superiority of either of the two procedures. In this study, 108 cirrhotic patients bleeding from varices were included in a prospective, randomized trial to invest

Randomized controlled trial of desmopres
Randomized controlled trial of desmopressin plus terlipressin vs. terlipressin alone for the treatment of acute variceal hemorrhage in cirrhotic patients: A multicenter, double-blind study
✍ Dr. Roberto de Franchis; Paolo G. Arcidiacono; Luca Carpinelli; Bruno Andreoni; πŸ“‚ Article πŸ“… 1993 πŸ› John Wiley and Sons 🌐 English βš– 702 KB

l-Deamino-8-D-arginine vasopressin (DDAVP, desmopressin), a synthetic analog of the antidiuretic hormone L-arginine vasopressin, improves hemostasis parameters in cirrhotic patients. Hence its use in combination with a vasoactive drug such as terlipressin might improve the performance of this drug i

Controlled trial of vasopressin plus nit
Controlled trial of vasopressin plus nitroglycerin vs. vasopressin alone in the treatment of bleeding esophageal varices
✍ Yang-Te Tsai; Chii-Shyan Lay; Kwok-Hung Lai; Wai-Wah Ng; Yeong-Shyan Yeh; Jiin-Y πŸ“‚ Article πŸ“… 1986 πŸ› John Wiley and Sons 🌐 English βš– 448 KB

Thirty-nine patients admitted during a 16-month period for acute bleeding from varices confirmed by emergency endoscopy were randomized to receive either continuous intravenous infusions of vasopressin alone (0.66 units per min) (Group I: 19 patients) or vasopressin plus sublingual nitroglycerin (0.