A randomized trial comparing mitoxantrone with doxorubicin in patients with stage IV breast cancer
โ Scribed by Joseph C. Allegra; T. Woodcock; S. Woolf; I. C. Henderson; Shelley Bryan; A. Reisman; Gary Dukart
- Publisher
- Springer US
- Year
- 1985
- Tongue
- English
- Weight
- 529 KB
- Volume
- 3
- Category
- Article
- ISSN
- 0167-6997
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
New agents with increased activity and/or reduced toxicity are needed for the treatment of advanced breast cancer. The anthracene derivatives mitoxantrone and bisantrene had significant activity and acceptable toxicity in phase II trials. In an ongoing phasc III trial we have now randomized 150 pati
## Abstract ## Background The laparoscopic treatment of rectal cancer is controversial. This study compared surgical outcomes after laparoscopic and open approaches for mid and low rectal cancers. ## Methods Some 204 patients with mid and low rectal adenocarcinomas were allocated randomly to ope
The chronopharmacokinetics of doxorubicin (DOX) has been studied in 18 patients suffering from breast cancer. They received combined chemotherapy including DOX (50 mg/m2 as an iv bolus), given at two different times (09.00 h or 21.00 h). The two randomized courses of the protocol were given to each