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A randomized, repeat-dose, pharmacodynamic and safety study of an antidote-controlled factor IXa inhibitor

✍ Scribed by M. Y. CHAN; C. P. RUSCONI; J. H. ALEXANDER; R. M. TONKENS; R. A. HARRINGTON; R. C. BECKER


Book ID
109152490
Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
315 KB
Volume
6
Category
Article
ISSN
1538-7933

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MLN3897 plus methotrexate in patients wi
✍ Clarissa E. Vergunst; Danielle M. Gerlag; Lisa von Moltke; Michael Karol; Tim Wy πŸ“‚ Article πŸ“… 2009 πŸ› John Wiley and Sons 🌐 English βš– 169 KB πŸ‘ 3 views

## Abstract ## Objective To assess the efficacy, safety, pharmacokinetics, and pharmacodynamics of the CC chemokine receptor CCR1 antagonist MLN3897 in patients with rheumatoid arthritis (RA) receiving methotrexate (MTX). ## Methods In this phase IIa, proof‐of‐concept study, patients meeting the