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A randomized phase II trial of adjuvant chemotherapy with uracil/tegafur and gemcitabine versus gemcitabine alone in patients with resected pancreatic cancer

✍ Scribed by Hideyuki Yoshitomi; Akira Togawa; Fumio Kimura; Hiroshi Ito; Hiroaki Shimizu; Hiroyuki Yoshidome; Masayuki Otsuka; Atsushi Kato; Satoshi Nozawa; Katsunori Furukawa; Masaru Miyazaki; Pancreatic Cancer Chemotherapy Program of the Chiba University Department of General Surgery Affiliated Hospital Group


Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
128 KB
Volume
113
Category
Article
ISSN
0008-543X

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## Abstract ## BACKGROUND The goals of the current study were to determine the safety and efficacy of a nonplatinum‐containing doublet, gemcitabine and docetaxel, in the treatment of patients with chemotherapy‐naive nonsmall cell lung carcinoma (NSCLC). ## METHODS Thirty‐two patients with advanc

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## Background: The combination of uracil and tegafur in a 4:1 molar concentration (uft) has a greater antitumor activity than 5-fluorouracil (5-fu) and tegafur. because the combination of 5-fu and cisplatin has been proven to have a synergistic antitumor effect in many experimental and clinical stu