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A randomized, double-blind, sponsor-unblinded, placebo- and positive-controlled study to evaluate the effects of single oral administrations of PF-04995274 on scopolamine-induced deficits in cognitive function in healthy adults

โœ Scribed by Leurent, Claire; Duvvuri, Sridhar; Raunig, David; Antinew, Jeremias; Rowinski, Carolyn; Zumpano, Laura; Bergeron, Michelle; Kocinsky, Hetal; Sieklucki, Joy; Nicolas, Timothy; Rapp, Tracey L.


Book ID
122919766
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
64 KB
Volume
8
Category
Article
ISSN
1552-5260

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A double-blind, placebo-controlled study
โœ C. R. Lines; J. H. Ambrose; A. Heald; M. Traub ๐Ÿ“‚ Article ๐Ÿ“… 1993 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 612 KB

This double-blind, placebo-controlled, crossover study examined the effects of two single doses of eptastigmine, a novel cholinesterase inhibitor, on scopolamine-induced cognitive deficits in 24 healthy male volunteers. Each subject received the following treatment sequences, separated by at least 1