## Abstract ## Background There have been very limited investigations of cholinesterase inhibitor therapy in more advanced stages of Alzheimer's disease (AD). The efficacy and safety of donepezil were evaluated in __post hoc__ analyses of a subgroup of patients with more severe AD (standardized Mi
A Randomized, Double-Blind, Placebo-Controlled Study of the Efficacy and Safety of Donepezil in Patients with Alzheimer's Disease in the Nursing Home Setting
β Scribed by Pierre N. Tariot; Jeffrey L. Cummings; Ira R. Katz; Jacobo Mintzer; Carlos A. Perdomo; Elias M. Schwam; Edward Whalen
- Book ID
- 109128207
- Publisher
- John Wiley and Sons
- Year
- 2001
- Tongue
- English
- Weight
- 249 KB
- Volume
- 49
- Category
- Article
- ISSN
- 0002-8614
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract ## Background Donepezil Hydrochloride (Aricept) is a selective anticholinesterase inhibitor developed for the treatment of Alzheimer's disease (AD). This study investigated the safety and efficacy of the drug to treat Down syndrome (DS) adults with mild to moderate AD. ## Method This
## Abstract ## Objective To examine the safety and efficacy of sertraline augmentation therapy in the treatment of behavioral manifestations of Alzheimer's disease (AD) in outpatients treated with donepezil. ## Methods and materials Patients with probable or possible AD, and a Neuropsychiatric I
Background. Metrifonate is a long-lasting acetylcholinesterase inhibitor being developed for the symptomatic treatment of Alzheimer's disease (AD). Objectives. This study compared the ecacy, tolerability and safety of two doses of metrifonate in patients with mild-to-moderate AD, over a 26-week tre