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A randomized, double-blind, placebo-controlled Phase 2 study of α4β2 agonist ABT-894 in adults with ADHD

✍ Scribed by Earle Bain; Weining Robieson; Tushar Garimella; Walid Abi-Saab; George Apostol; Mario D. Saltarelli


Book ID
113489606
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
53 KB
Volume
82
Category
Article
ISSN
0006-2952

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In nonalcoholic steatohepatitis (NASH), the extent of hepatocyte apoptosis correlates with disease severity. Reducing hepatocyte apoptosis with the selective caspase inhibitor GS-9450 has a potential for altering the course of the liver disease. In this phase 2, double-blind study, 124 subjects with