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A randomized, double-blind, placebo-controlled dose-finding trial of intravenous immunoglobulin (IVIG; Octagam® 10%, Octapharma AG) in patients with mild to moderate Alzheimer's disease (GAM10-04)

✍ Scribed by Dodel, Richard; Rominger, Axel; Blennow, Kaj; Barkhof, Frederik; Wietek, Stefan; Haag, Stefan; Bartenstein, Peter; Farlow, Martin; Jessen, Frank


Book ID
122524445
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
87 KB
Volume
7
Category
Article
ISSN
1552-5260

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Background. Metrifonate is a long-lasting acetylcholinesterase inhibitor being developed for the symptomatic treatment of Alzheimer's disease (AD). Objectives. This study compared the ecacy, tolerability and safety of two doses of metrifonate in patients with mild-to-moderate AD, over a 26-week tre