✦ LIBER ✦
A randomized clinical study of calcium-entry blocker (lidoflazine) in the treatment of comatose survivors of cardiac arrest: Brain Resuscitation Clinical Trial II Study Group N Engl J Med 324:1225–1231 May 1991
✍ Scribed by Andrew Johanos
- Publisher
- Elsevier Science
- Year
- 1991
- Tongue
- English
- Weight
- 240 KB
- Volume
- 20
- Category
- Article
- ISSN
- 1097-6760
No coin nor oath required. For personal study only.
✦ Synopsis
WBC cutoff of 5,000/mm 3 had 100% sensitivity and 7% specificity. A cutoff of 10,000/mm 3 was thought to be optimal, with a 92% sensitivity, 43% specificity, and a 5% PPV. Based on the results of this study, the authors recommend that if the examiner wishes to use a CBC as a screening procedure, then blood cultures should be obtained on all children between 3 and 36 months of age with temperatures of 39.0 C or more and WBC of more than 10,000/mm 3.