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A randomised phase II study on neo-adjuvant chemotherapy for ‘high-risk’ adult soft-tissue sarcoma

✍ Scribed by E Gortzak; A Azzarelli; J Buesa; V.H.C Bramwell; F van Coevorden; A.N van Geel; A Ezzat; A Santoro; J.W Oosterhuis; M van Glabbeke; A Kirkpatrick; J Verweij


Book ID
117657205
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
158 KB
Volume
37
Category
Article
ISSN
0959-8049

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In a phase II study, 16 adult patients with locally advanced or metastatic soft tissue sarcomas were treated with i.v. infusions of ifosfamide/mesna 5 g/m2 plus i.v. doxorubicin 40 mg/m2. Courses were given every 3 weeks up to a maximum of six courses in responding patients. Six patients (37.5%) had