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A randomised double-blind placebo-controlled trial of the impact of high-dose statins on the ischaemia-reperfusion injury in elective AAA repair

✍ Scribed by M. N. A. Abdul Rahman; M. Heng; L. Madden; J. Greenman; P. T. McCollum; I. C. Chetter

Publisher: John Wiley and Sons
Year: 2009
Tongue: English
Weight: 71 KB
Volume: 96
Category: Article
ISSN: 0007-1323
DOI: 10.1002/bjs.6500

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✦ Synopsis

4 VSGBI abstracts

(→ = +0•56, p = 0•003 and → = +0•38, p < 0•0•001, respectively). RCF had an independent inverse correlation with bk-PWV (→ = -0•01, p = 0•01). Systolic blood pressure showed an independent positive correlation with ba-PWV only after adjustment for other biomarkers (→ = +0•1, p = 0•04). Cholesterol/HDL had an independent inverse correlation with ABPI (→ = -0•08, p = 0•046). There was no significant association between the other biomarkers and ABPI or PWV. Conclusion: Hypercholesterolaemia and hypertension need aggressive treatment in this population. Plasma Hcy and RCF levels correlated well with severity of PAD. They are easily measured markers of disease and provide possible targets for further risk factor modification.

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