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A radiometric assay for determining the incorporation of l-canavanine or l-arginine into protein

✍ Scribed by Gerald A. Rosenthal; Deborah A. Thomas


Publisher
Elsevier Science
Year
1985
Tongue
English
Weight
362 KB
Volume
147
Category
Article
ISSN
0003-2697

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✦ Synopsis


Procedures for a radiometric assay of L-[guanidinooxy-14C]canavanine were developed which provide a convenient and accurate measure of the incorporation of [14C]canavanine into de novo-synthesized proteins. These methods are also applicable to determining [14C]arginine incorporation into protein. These procedures have been employed to study the synthesis of L-[guanidinooxy-14C]canavanine- and L-[guanidino-14C]arginine-containing proteins from the hemolymph of Manduca sexta and Heliothis virescens, two highly destructive insect pests.