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A Radiation Hybrid Map of 48 Loci Including the Clouston Hidrotic Ectodermal Dysplasia Locus in the Pericentromeric Region of Chromosome 13q

✍ Scribed by Zoha Kibar; Ronald G. Lafrenière; Aravinda Chakravarti; Jia-Chi Wang; Mario Chevrette; Vazken M. Der Kaloustian; Guy A. Rouleau


Book ID
115614628
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
59 KB
Volume
56
Category
Article
ISSN
0888-7543

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The gene for autosomal dominant hidrotic
✍ Radhakrishna, Uppala; Blouin, Jean-Louis; Mehenni, Hamid; Mehta, Timir Y.; Sheth 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 53 KB 👁 2 views

Hidrotic ectodermal dysplasia (HED), Clouston syndrome (MIM No. 129500), is an autosomal dominant disorder affecting the skin and its derivatives. It is characterized by alopecia, dysplastic nails in hands and feet, and hyperkeratosis of the palms and soles. We have studied a large Indian pedigree (