𝔖 Bobbio Scriptorium
✦   LIBER   ✦

A quantitative study of physiological cerebral atrophy with aging

✍ Scribed by K. Nagata; N. Basugi; T. Fukushima; T. Tango; I. Suzuki; T. Kaminuma; S. Kurashina


Book ID
104733969
Publisher
Springer
Year
1987
Tongue
English
Weight
762 KB
Volume
29
Category
Article
ISSN
0028-3940

No coin nor oath required. For personal study only.

✦ Synopsis


A new method of discriminating pathological cerebral atrophy from physiological atrophy during aging is reported. The authors advocate a pixel counting method using a minicomputer for the quantitative measurement of cerebral atrophy. Five hundred cases were studied with this quantitative method and the normal range of the physiological atrophy was determined statistically. In order to estimate the degree of cerebral atrophy easily, the conventional linear measurement methods were compared with the pixel counting method using multivariant analysis, and a simple formula for the calculation of the degree of cerebral atrophy is proposed. Using this formula and the normal range, pathological cerebral atrophy is easily detectable.


πŸ“œ SIMILAR VOLUMES


Astrocyte changes in aging cerebral cort
✍ Amenta, Francesco; Bronzetti, Elena; Sabbatini, Maurizio; Vega, JosΓ© Antonio πŸ“‚ Article πŸ“… 1998 πŸ› John Wiley and Sons 🌐 English βš– 168 KB

Glial cells are sensitive to aging, but the real extent of age-related quantitative and qualitative changes of these brain cellular elements has not yet been clarified. Brain volume undergoes age-related changes, but several studies on the number of glial cells have not taken this important variable

A quantitative study of lipofuscin accum
✍ Christopher D. West πŸ“‚ Article πŸ“… 1979 πŸ› John Wiley and Sons 🌐 English βš– 619 KB

## Abstract The amount of lipofuscin in neurons of two brainstem nuclei, the inferior olivary nucleus (ION) and the lateral geniculate nucleus (LGN), was measured in the brains of 1 progeric, 2 phenylketonuric, 5 Down's syndrome and 13 normal individuals. Aggregations of lipofuscin granules in cres